Politécnicos hallan en planta considerada maleza un compuesto anticancerígeno.

by / 245 Comments / 10 View / 08/08/2017

Investigadores de la ESM estudian molécula terpeno, que se encuentra en un a especie llamada chan, presente en varias regiones del país. Ha sido efectiva contra células de varios cánceres

Investigadores del IPN hallaron una molécula con actividad anticancerígena en una planta llamada Hyptis suaveolens, conocida como chan o chía cimarrona, un tipo de maleza que en el sureste se emplea en la medicina tradicional. Los investigadores politécnicos estudian los compuestos de la planta para obtener productos farmacéuticos que en el futuro puedan emplearse clínicamente.

José Rubén García Sánchez, investigador del Laboratorio de oncología molecular y estrés oxidativo de la Escuela Superior de Medicina (ESM) del IPN, encabeza la investigación que consistió en la obtención de un componente orgánico llamado terpeno, cuyo efecto han estudiado en cultivos celulares de cáncer de mama.

La planta tiene registros como medicamento tradicional desde el siglo XVI, donde el  Códice Florentinorefiere el uso de su semilla para las “carencias de cámaras” (diarrea).

De acuerdo con la Comisión Nacional para el Conocimiento y Uso de la Biodiversidad (Conabio), la planta tiene propiedades insecticidas y contiene varios aceites esenciales, los cuales pueden ser variados entre poblaciones. También se tiene registrado que tiene propiedades antimicrobianas, antifúngicas, hipoglicémicas, antiinflamatorias y antioxidantes.

La planta se distribuye en el país y hasta Sudamérica; en Chiapas, acota el investigador, la usan como tratamiento contra el cáncer, la venden o regalan contra cualquier tipo de cáncer. A raíz de este acercamiento del uso tradicional, el investigador politécnico señala que se interesaron por investigar la planta y hacer un estudio biodirigido para comprobar sus efectos.

En entrevista, García Sánchez señala que trabajan con las hojas de la planta, que dejan secar para realizar extractos con diversos solventes, lo que deja un residuo donde buscan la molécula que han probado tiene efecto en cultivos celulares de cáncer.

Así aislaron una molécula terpeno, cuyo efecto han probado en células cancerosas de mama, pulmón, estomago y próstata. Adicionalmente han probado que tiene una actividad selectiva y no afecta otras células que no sean cancerosas.

El estudio inició hace alrededor de cinco años, con investigadores y financiamiento del Politécnico, cuyos logros importantes son haber obtenido la molécula y haber probado su efectividad. Su estudio debe continuar para conocer qué mecanismo es el que genera una acción contra las células cancerosas; han probado, por ejemplo, que no genera un proceso de autodestrucción llamado apoptosis. “Tenemos algunos indicios y evidencias sobre cuál sería el mecanismo, pero lo tenemos que corroborar. No es sencillo hacer estos estudios, por eso es importante obtener la molécula”.

Para ello, los investigadores emprenderán una campaña de recolección de la planta, para después obtener los extractos de la molécula y continuar la obtención de su estructura química, lo cual permitirá ahondar en el conocimiento sobre su efecto en las células cancerosas.

También continuarán sus estudios sobre toxicidad y efectos en modelos animales, estudios que se acelerarían de contar con financiamiento externo, como del Conacyt, acotó.

Desde hace alrededor de ocho años, los científicos del Politécnico emprendieron sus estudios en otro compuesto llamado epicatequina, presente en el chocolate, vinos y té verde, también en la búsqueda de aplicarla contra cáncer. Ese compuesto se había estudiado en enfermedades cardiovasculares y su efecto protector en infarto y procesos de hipertensión, pero no en cáncer.

El investigador señala que el objetivo de su grupo de investigación es hacer estudios de mediano y largo plazo para que tengan un efecto en la sociedad. “Queremos ofrecer nuevas opciones terapéuticas a las existentes, menos agresivas y de origen natural”.

Redacción: Crónica

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  189. Conceição comentou em 6 de junho de 2012 às 13:54. Oi, eu usava Roacutan e tinha os labios muito ressecados e pra completar me mudei pra luxemburgo durante o inverno ai foi um desastre total, ja usava o Bepantol mas não tava dando jeito, entao comecei a usar o baume para os labios da Sisley, ele custa uns 30€ mas dura uma eternidade e foi a minha salvação aqui!!!

  190. On the upside, OmegaTube does have a pretty OK link list of movies with relatively high quality – so if you’ve got more than 21 minutes to kill, it might be worth your time to scroll through their movies and check out what you would be otherwise spending your hard-earned moolah on at the local Blockbuster Video (or NetFlix, if you still like that kinda stuff).

  191. Field, I’m so sorry for you. I’m sorry for me. I’m sorry for all of us.I need to check the death toll here in Houston too. People are getting shot up so much out here, that I’m reminded of the crack days back in the late80’s-early 90’s. I’m going to find out what our toll is and let you know.Peace, my brotha.Angie

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  196. gizmolina skriver:Haha. Allt var aldrig tänkt att få plats. Det mesta var beställningar från fina kunder så det mesta hämtades i går. Kram !

  197. Do is a fine, wonderful lady. I echo Dan’s comments about her, about Jim, and about their wonderful children/family. And yes, the Bacharach family is a splendid example of what is best about Westport.

  198. cindy pennybacker – I knew when I met you that I had found a truly beautiful person. I am so happy to know you and David and those gorgeous babies! I can’t wait the meet the next one! You’re work is a clear display of your talent and your heart. xoxo

  199. A good product but does one really need it? No the pen tool the tablet comes with does the same thing. So is it worth the 100.00 for a cool toy? Sure I love cool toys and can afford to buy them. On a budget just use the pen tool it can also be set up just like the airbrush in your software.

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  203. Babel, Phil, Babel et sa bibliothèque (la fnac dans l’antiquité)… Quelle félicité ce serait, ou quel cauchemar…! Comme le dit Rousseau dans sa Cinquième promenade : « De quoi jouit-on dans une pareille situation ? De rien d’extérieur à soi, de rien sinon de soi-même et de sa propre existence, tant que cet état dure on se suffit à soi-même comme Dieu. » Et comme dit JC, Arrêtez Moi !

  204. What a great post! I pray this very thing for our youth today! It seems that they struggle so much with the world’s influences more than ever.I pray that you are doing well. Have a wonderful week!

  205. gent. mistrel,18:21mi permetto di dire che secondo me, la ricerca intellettuale sulle* ragioni della fede* non necessariamente porta a capirle, e di riflesso,alla fede stessa,se non interpreto male le sue parole.Ho una mia versione, sulla motivazione di quelle ragioni, che mi porta a capirle ma non a capire la fede,anzi LE fedi,dato che ve ne sono tante e di diverse forme.saluti

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  209. HARD CORE CYCLISTS!!! YOU ALL ROCK!Jim, your storm in Portland made the national news. We had 15+ foot swells from your storm generating large 20 waves crashing against our coast beginning yesterday, and we're supposed to get your rain on Thursday.Yam: I hear you. My co-workers would skip work to go skiing on fresh power days, after enduring a four hour drive just to get to the better ski areas. Our winter sport is built into the commute

  210. Thanks, Cathy! I keep trying to be healthy…the walking is really making me feel good. Lists always help me when we’re getting ready for one of these trips. You know, the idea of walking around the house isn’t a bad one, only problem is it’s on a hill…a Real hill and i don’t think I could do the back yard area, too steep, but I might figure something out! Have a great day!

  211. Interesting… I actually felt like overall, New Vegas had less built-in sexism, or at least a less built-in male viewpoint, than Fallout 3 did. Caesar’s Legion are of course horribly misogynistic, but they’re also just flat out terrible people, and I always figured that their “no girls allowed” stance was meant to be an indicator of how backwards and dreadful they are.There are certainly places to quibble, or problem elements — Gomorrah, that one lesbian PTSD soldier in the NCR — but I feel like in general, the tone and worldview weren’t too bad on the sexism front.

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  238. week, I gave you ideas about how to replenish your heart chakra. Today, I’m going to talk about another common way your energy system may be affected by grief,

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  242. « les “idées préconçues” ce que vous disiez : “pour découvrir un monde plus complexe et plus profond que je l’avais décidé”. »Ouf, Sapience. Et j’ai donné la preuve, tatatam, que je peux abandonner des idées préconçues. ML,c’est quand tu veux !Gaspard, Ramile était un posteur tellement reconnaissable (je n’ai pas dit prévisible) que s’ilrevenit, même en se pseudonymisabt Frigide fa

  243. Hola Starviewer,aprovechando que se vuelve a tocar el tema de la enanita marrón, quiero volver a hacer una pregunta que formulé el 2009, y que quedo sin responder, sobre la contracción gravitatoria del 41% prevista por Murray , Matese y Oppenhheimer.¿Podrías explicarme de manera simple qué significa y cómo le puede afectar este fenómeno a la vida en la Tierra?Aclaro que no soy físico, ni tengo formación científica alguna.Saludos y gracias desde ya.

  244. Bueno, bueno… Con que ilusión y pensando en nuestros hermanos de Kenia hacéis que nos sintamos orgullosos de todo este gran traballo que lleváis adelante. Gracias por compartir con las delegaciones vuestros proyectos y hacer posible que Kenia pueda tener más vida. Gracias por ser esperanza y futuro. Rosalía.

  245. Hi! I’ve been drinking a lot of water at school lately but for some reason (even though I work out 5-6 days a week) my muscle keeps getting looser. Do you by chance have an explanation for that? 🙂 thanks!

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